Coatings with ceramic-metal, ceramic-ceramic or even ceramic-polymer interfaces are also be of major emphasis with application specific design concepts such as functional optical coatings. A very good example to such an approach is the quantum well and quantum dot structures that give unique response to light stimulation when in contact with various biological molecules. The properties of quantum dots and wells depend on the interfaces they possess with their local environments and the properties of this environment can be changed in a controlled manner tailoring organic-inorganic and inorganic-inorganic interface interactions for detection.